Hello, this is Ilwon Station Exit 1 Pharmacy!
Today, I will explain in detail about Dudrizin Syrup (hydroxyzine hydrochloride), one of the medicines frequently prescribed to pediatric patients at the nearby Samsung Seoul Hospital.
I have also included information that those suffering from diseases such as allergies, anaphylaxis, rhinitis, and eczema may be curious about, so
please read comfortably!
Mechanism of action of Dudrin syrup (ingredient: hydroxyzine)
Hydroxyzine, the main ingredient of Dudrin syrup, belongs to a group of drugs called antihistamines.
In simple terms, it blocks histamine, which causes allergic reactions.
Histamine causes symptoms such as rhinitis, hives, and eczema, but hydroxyzine suppresses this and reduces itching and inflammation.
It also has a mild calming effect on the brain and spinal cord, so it helps relieve anxiety, tension, and nervousness.
So it is a medicine that can be prescribed not only for allergies but also for sensitive nerves.
Pharmacokinetics: Onset, Duration, Absorption
Hydroxyzine's pharmacokinetics tell us how the drug works in the body.
- Onset: When taken orally, it takes effect within 15 to 30 minutes.
Itching is relieved or the mind becomes calm soon after taking it.
- Duration: The effect lasts for 4 to 6 hours. This is why it is taken 2 to 3 times a day.
- Absorption: When taken orally, it is absorbed quickly. It enters the bloodstream quickly through the stomach and intestines.
This characteristic allows it to be quickly helped when itching at night.
Dosage by age
Dosage varies depending on age and symptoms.
In particular, since the pediatric dosage is not specified in the domestic approval,
we will explain it through foreign data (source: www.mayoclinic.org).
Please follow the doctor's instructions for dosage and frequency of administration!
Adults
▶ Anxiety, tension ▶ Take 50 mg three times a day (12.5 mg, 12.5 mg, 25 mg). Up to 100 mg is possible.
▶ Hives, itching ▶ Take 30-60 mg two to three times a day.
▶ Elderly ▶ Start with half the adult dosage because the drug may be excreted slowly from the body. The maximum daily dose is 50 mg.
Pediatric
There is no dosage or administration for children in the Dudrin syrup license, so foreign literature was referenced.
★ Children 6 years of age or older ★
For allergy treatment and management, 50 to 100 mg of hydroxyzine is administered in divided doses per day. Since Dudrin syrup is 2 mg/mL, divide 25 to 50 mL per day.
★ Children under 6 years of age ★
50 mg is administered in divided doses per day. 25 mL of Dudrin syrup (2 mg/mL) is administered per day.
★ Based on weight ★
Generally, 0.5 to 1 mg/day per 1 kg of body weight is the standard.
For example, a 20 kg child can be divided into 10 to 20 mg (5 to 10 mL) per day.
However, please consult your doctor and prescription (instructions) for the exact dosage.
Indications (Efficacy)
Dudurizin syrup is used in the following cases:
1. Postoperative anxiety, tension: Reduces psychological anxiety.
2. Neurosis: Relieves excessive worry or nervousness.
3. Hives, eczema, dermatitis: Reduces itching caused by allergies.
It is often prescribed especially to those suffering from allergic reactions or skin diseases.
Side effects
You should also be aware of the side effects.
※ Drowsiness ※
It may make you drowsy because it calms the brain. Avoid driving.
※ Dry mouth ※
It will get better if you drink water often.
※ Constipation or indigestion ※
It may occur rarely.
※ Headache, dizziness ※
It may occur as the body adapts.
Why should it be stored in a light-proof container?
Dudurizin syrup should be stored in a light-proof container (brown bottle that does not allow light).
The medicine may decompose or become less effective if exposed to light.
Ilwon Station Exit 1 Pharmacy will put it in a brown bottle, so keep it in a cool, dark place at home.
Additional information that patients are curious about
★ Allergy and anaphylaxis
It reduces allergy symptoms, but if you are allergic to the medicine itself, anaphylaxis may occur in rare cases.
★ Comparison of Ucerax Syrup and Dudrizine Syrup
These are products with the same ingredientsd
Especially for children, you should follow the doctor's prescription carefully, considering weight and age. If you have any questions, please ask the pharmacy at Exit 1 of Ilwon Station at any time. We support your health!
